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Oral and Conjunctival Exposure of Nonhuman Primates to Low Doses of Ebola Makona Virus

Nonhuman primate (NHP) models of Ebola virus (EBOV) infection primarily use parenteral or aerosol routes of exposure. Uniform lethality can be achieved in these models at low doses of EBOV (≤100 plaque-forming units [PFU]). Here, we exposed NHPs to low doses of EBOV (Makona strain) by the oral or co...

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Detalles Bibliográficos
Autores principales: Mire, Chad E., Geisbert, Joan B., Agans, Krystle N., Deer, Daniel J., Fenton, Karla A., Geisbert, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050459/
https://www.ncbi.nlm.nih.gov/pubmed/27284090
http://dx.doi.org/10.1093/infdis/jiw149