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Cross-inhibition of pathogenic agents and the host proteins they exploit

The major limitations of pathogen-directed therapies are the emergence of drug-resistance and their narrow spectrum of coverage. A recently applied approach directs therapies against host proteins exploited by pathogens in order to circumvent these limitations. However, host-oriented drugs leave the...

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Detalles Bibliográficos
Autores principales: Zilbermintz, Leeor, Leonardi, William, Tran, Sharon H., Zozaya, Josue, Mathew-Joseph, Alyssa, Liem, Spencer, Levitin, Anastasia, Martchenko, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050486/
https://www.ncbi.nlm.nih.gov/pubmed/27703274
http://dx.doi.org/10.1038/srep34846