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Degradation of Redox-Sensitive Proteins including Peroxiredoxins and DJ-1 is Promoted by Oxidation-induced Conformational Changes and Ubiquitination

Reactive oxygen species (ROS) are key molecules regulating various cellular processes. However, what the cellular targets of ROS are and how their functions are regulated is unclear. This study explored the cellular proteomic changes in response to oxidative stress using H(2)O(2) in dose- and recove...

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Detalles Bibliográficos
Autores principales: Song, In-Kang, Lee, Jae-Jin, Cho, Jin-Hwan, Jeong, Jihye, Shin, Dong-Hae, Lee, Kong-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050490/
https://www.ncbi.nlm.nih.gov/pubmed/27703196
http://dx.doi.org/10.1038/srep34432