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4-Аminopyridine sequesters intracellular Ca(2+) which triggers exocytosis in excitable and non-excitable cells
4-aminopyridine is commonly used to stimulate neurotransmitter release resulting from sustained plasma membrane depolarization and Ca(2+)-influx from the extracellular space. This paper elucidated unconventional mechanism of 4-aminopyridine-stimulated glutamate release from neurons and non-neuronal...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050491/ https://www.ncbi.nlm.nih.gov/pubmed/27703262 http://dx.doi.org/10.1038/srep34749 |