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Unambiguous observation of blocked states reveals altered, blocker-induced, cardiac ryanodine receptor gating
The flow of ions through membrane channels is precisely regulated by gates. The architecture and function of these elements have been studied extensively, shedding light on the mechanisms underlying gating. Recent investigations have focused on ion occupancy of the channel’s selectivity filter and i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050499/ https://www.ncbi.nlm.nih.gov/pubmed/27703263 http://dx.doi.org/10.1038/srep34452 |