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Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity

Gallic acid, a type of phenolic acid, has been shown to have beneficial effects in inflammation, vascular calcification, and metabolic diseases. The present study was aimed at determining the effect and regulatory mechanism of gallic acid in cardiac hypertrophy and fibrosis. Cardiac hypertrophy was...

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Detalles Bibliográficos
Autores principales: Ryu, Yuhee, Jin, Li, Kee, Hae Jin, Piao, Zhe Hao, Cho, Jae Yeong, Kim, Gwi Ran, Choi, Sin Young, Lin, Ming Quan, Jeong, Myung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050511/
https://www.ncbi.nlm.nih.gov/pubmed/27703224
http://dx.doi.org/10.1038/srep34790