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Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity
Gallic acid, a type of phenolic acid, has been shown to have beneficial effects in inflammation, vascular calcification, and metabolic diseases. The present study was aimed at determining the effect and regulatory mechanism of gallic acid in cardiac hypertrophy and fibrosis. Cardiac hypertrophy was...
Autores principales: | Ryu, Yuhee, Jin, Li, Kee, Hae Jin, Piao, Zhe Hao, Cho, Jae Yeong, Kim, Gwi Ran, Choi, Sin Young, Lin, Ming Quan, Jeong, Myung Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050511/ https://www.ncbi.nlm.nih.gov/pubmed/27703224 http://dx.doi.org/10.1038/srep34790 |
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