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Crystal structure and DNA binding activity of a PadR family transcription regulator from hypervirulent Clostridium difficile R20291

BACKGROUND: Clostridium difficile is a spore-forming obligate anaerobe that can remain viable for extended periods, even in the presence of antibiotics, which contributes to the persistence of this bacterium as a human pathogen during host-to-host transmission and in hospital environments. We examin...

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Detalles Bibliográficos
Autores principales: Isom, Catherine E., Menon, Smita K., Thomas, Leonard M., West, Ann H., Richter-Addo, George B., Karr, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050560/
https://www.ncbi.nlm.nih.gov/pubmed/27716049
http://dx.doi.org/10.1186/s12866-016-0850-0