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High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD – results from the ECLIPSE study
BACKGROUND: There is a need to identify individuals with COPD at risk for disease progression and mortality. Lung tissue remodeling is associated with the release of extracellular matrix (ECM) fragments into the peripheral circulation. We hypothesized that ECM remodeling was associated with mortalit...
Autores principales: | Sand, Jannie M. B., Leeming, Diana J., Byrjalsen, Inger, Bihlet, Asger R., Lange, Peter, Tal-Singer, Ruth, Miller, Bruce E., Karsdal, Morten A., Vestbo, Jørgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050854/ https://www.ncbi.nlm.nih.gov/pubmed/27716343 http://dx.doi.org/10.1186/s12931-016-0440-6 |
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