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A novel DNA/histone H4 peptide complex detects autoantibodies in systemic lupus erythematosus sera
BACKGROUND: The detection of anti-dsDNA antibodies is critical for the diagnosis and follow-up of systemic lupus erythematosus (SLE) patients. The presently available assays are characterized by a non-optimal specificity (solid phase assays) or sensitivity (Crithidia Luciliae immunofluorescence test...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050916/ https://www.ncbi.nlm.nih.gov/pubmed/27716380 http://dx.doi.org/10.1186/s13075-016-1117-8 |