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A novel DNA/histone H4 peptide complex detects autoantibodies in systemic lupus erythematosus sera

BACKGROUND: The detection of anti-dsDNA antibodies is critical for the diagnosis and follow-up of systemic lupus erythematosus (SLE) patients. The presently available assays are characterized by a non-optimal specificity (solid phase assays) or sensitivity (Crithidia Luciliae immunofluorescence test...

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Detalles Bibliográficos
Autores principales: Panza, Filomena, Alcaro, Maria Claudia, Petrelli, Fiorella, Angelotti, Francesca, Pratesi, Federico, Rovero, Paolo, Migliorini, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050916/
https://www.ncbi.nlm.nih.gov/pubmed/27716380
http://dx.doi.org/10.1186/s13075-016-1117-8