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Hepatoprotective Property of Oral Silymarin is Comparable to N-Acetyl Cysteine in Acetaminophen Poisoning

BACKGROUND: N-Acetyl Cysteine (NAC) is usually used as antidote for prevention of acetaminophen-induced hepatotoxicity. In present study we have evaluated efficacy of oral silymarin in its prevention in rats intoxicated with lethal dose of acetaminophen. METHODS: A total of 50 Male Sprague-Dawley ra...

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Detalles Bibliográficos
Autores principales: Kazemifar, Amir Mohammad, Hajaghamohammadi, Ali Akbar, Samimi, Rasoul, Alavi, Zohreh, Abbasi, Esmail, Asl, Marjan Nasiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051100/
https://www.ncbi.nlm.nih.gov/pubmed/27785204
http://dx.doi.org/10.4021/gr463e