SMARCAL1 Resolves Replication Stress at ALT Telomeres

Cancer cells overcome replicative senescence by exploiting mechanisms of telomere elongation, a process often accomplished by reactivation of the enzyme telomerase. However, a subset of cancer cells lack telomerase activity and rely on the alternative lengthening of telomeres (ALT) pathway, a recomb...

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Detalles Bibliográficos
Autores principales: Cox, Kelli E., Maréchal, Alexandre, Flynn, Rachel Litman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051350/
https://www.ncbi.nlm.nih.gov/pubmed/26832416
http://dx.doi.org/10.1016/j.celrep.2016.01.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051350/
https://www.ncbi.nlm.nih.gov/pubmed/26832416
http://dx.doi.org/10.1016/j.celrep.2016.01.011

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