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SMARCAL1 Resolves Replication Stress at ALT Telomeres

Cancer cells overcome replicative senescence by exploiting mechanisms of telomere elongation, a process often accomplished by reactivation of the enzyme telomerase. However, a subset of cancer cells lack telomerase activity and rely on the alternative lengthening of telomeres (ALT) pathway, a recomb...

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Detalles Bibliográficos
Autores principales:	Cox, Kelli E., Maréchal, Alexandre, Flynn, Rachel Litman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051350/ https://www.ncbi.nlm.nih.gov/pubmed/26832416 http://dx.doi.org/10.1016/j.celrep.2016.01.011

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