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Enhancement of viral escape in HIV-1 Nef by STEP vaccination

Properly priming cytotoxic T-lymphocyte (CTL) responses is an important task in HIV-1 vaccination. However, the STEP trial showed no efficacy even though the vaccine elicited HIV-specific CTL responses. Our study is to investigate whether or not the STEP vaccine enhanced viral escape in infected vol...

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Detalles Bibliográficos
Autores principales: Park, Sung Yong, Mack, Wendy J., Lee, Ha Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051524/
https://www.ncbi.nlm.nih.gov/pubmed/27427874
http://dx.doi.org/10.1097/QAD.0000000000001202