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Programed death-1/programed death-ligand 1 expression in lymph nodes of HIV infected patients: results of a pilot safety study in rhesus macaques using anti–programed death-ligand 1 (Avelumab)

The programed death-1 (PD1)/programed death-ligand 1 (PD-L1) pathway plays a critical role in balancing immunity and host immunopathology. During chronic HIV/SIV infection, there is persistent immune activation accompanied by accumulation of virus-specific cells with terminally differentiated phenot...

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Detalles Bibliográficos
Autores principales: Gill, Amanda L., Green, Samantha A., Abdullah, Shahed, Le Saout, Cecile, Pittaluga, Stefania, Chen, Hui, Turnier, Refika, Lifson, Jeffrey, Godin, Steven, Qin, Jing, Sneller, Michael C., Cuillerot, Jean-Marie, Sabzevari, Helen, Lane, H. Clifford, Catalfamo, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051527/
https://www.ncbi.nlm.nih.gov/pubmed/27490642
http://dx.doi.org/10.1097/QAD.0000000000001217