Fraxetin Induces Heme Oxygenase-1 Expression by Activation of Akt/Nrf2 or AMP-activated Protein Kinase α/Nrf2 Pathway in HaCaT Cells

BACKGROUND: Fraxetin (7,8-dihydroxy-6-methoxy coumarin), a coumarin derivative, has been reported to possess antioxidative, anti-inflammatory and neuroprotective effects. A number of recent observations suggest that the induction of heme oxygenase-1 (HO-1) inhibits inflammation and tumorigenesis. In...

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Detalles Bibliográficos
Autores principales: Kundu, Juthika, Chae, In Gyeong, Chun, Kyung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051587/
https://www.ncbi.nlm.nih.gov/pubmed/27722139
http://dx.doi.org/10.15430/JCP.2016.21.3.135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051587/
https://www.ncbi.nlm.nih.gov/pubmed/27722139
http://dx.doi.org/10.15430/JCP.2016.21.3.135

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