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Critical importance of appropriate fixation conditions for faithful imaging of receptor microclusters

Receptor clustering is known to trigger signalling events that contribute to critical changes in cellular functions. Faithful imaging of such clusters by means of fluorescence microscopy relies on the application of adequate cell fixation methods prior to immunolabelling in order to avoid artefactua...

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Detalles Bibliográficos
Autores principales: Stanly, Tess A., Fritzsche, Marco, Banerji, Suneale, García, Esther, Bernardino de la Serna, Jorge, Jackson, David G., Eggeling, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051640/
https://www.ncbi.nlm.nih.gov/pubmed/27464671
http://dx.doi.org/10.1242/bio.019943