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Fourth-Generation Progestins Inhibit 3β-Hydroxysteroid Dehydrogenase Type 2 and Modulate the Biosynthesis of Endogenous Steroids

Progestins used in contraception and hormone replacement therapy are synthetic compounds designed to mimic the actions of the natural hormone progesterone and are classed into four consecutive generations. The biological actions of progestins are primarily determined by their interactions with stero...

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Detalles Bibliográficos
Autores principales: Louw-du Toit, Renate, Perkins, Meghan S., Snoep, Jacky L., Storbeck, Karl-Heinz, Africander, Donita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051719/
https://www.ncbi.nlm.nih.gov/pubmed/27706226
http://dx.doi.org/10.1371/journal.pone.0164170