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The Production of a Stable Infliximab Powder: The Evaluation of Spray and Freeze-Drying for Production
In prospect of developing an oral dosage form of Infliximab, for treatment of Crohn’s disease and rheumatoid arthritis, freeze-drying (vial vs Lyoguard trays) and spray-drying were investigated as production method for stable powders. Dextran and inulin were used in combination with sucrose as stabi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051734/ https://www.ncbi.nlm.nih.gov/pubmed/27706175 http://dx.doi.org/10.1371/journal.pone.0163109 |