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The Production of a Stable Infliximab Powder: The Evaluation of Spray and Freeze-Drying for Production

In prospect of developing an oral dosage form of Infliximab, for treatment of Crohn’s disease and rheumatoid arthritis, freeze-drying (vial vs Lyoguard trays) and spray-drying were investigated as production method for stable powders. Dextran and inulin were used in combination with sucrose as stabi...

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Detalles Bibliográficos
Autores principales:	Kanojia, Gaurav, Have, Rimko ten, Bakker, Arjen, Wagner, Koen, Frijlink, Henderik W., Kersten, Gideon F. A., Amorij, Jean-Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051734/ https://www.ncbi.nlm.nih.gov/pubmed/27706175 http://dx.doi.org/10.1371/journal.pone.0163109

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