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Identification of Unanticipated and Novel N-Acyl L-Homoserine Lactones (AHLs) Using a Sensitive Non-Targeted LC-MS/MS Method

N-acyl L-homoserine lactones (AHLs) constitute a predominant class of quorum-sensing signaling molecules used by Gram-negative bacteria. Here, we report a sensitive and non-targeted HPLC-MS/MS method based on parallel reaction monitoring (PRM) to identify and quantitate known, unanticipated, and nov...

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Detalles Bibliográficos
Autores principales: Patel, Nishaben M., Moore, Joseph D., Blackwell, Helen E., Amador-Noguez, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051804/
https://www.ncbi.nlm.nih.gov/pubmed/27706219
http://dx.doi.org/10.1371/journal.pone.0163469