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Influence of Different Levels of Lipoic Acid Synthase Gene Expression on Diabetic Nephropathy

Oxidative stress is implicated in the pathogenesis of diabetic nephropathy (DN) but outcomes of many clinical trials are controversial. To define the role of antioxidants in kidney protection during the development of diabetic nephropathy, we have generated a novel genetic antioxidant mouse model wi...

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Detalles Bibliográficos
Autores principales: Xu, Longquan, Hiller, Sylvia, Simington, Stephen, Nickeleit, Volker, Maeda, Nobuyo, James, Leighton R., Yi, Xianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051822/
https://www.ncbi.nlm.nih.gov/pubmed/27706190
http://dx.doi.org/10.1371/journal.pone.0163208