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Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease worldwide but current treatments remain suboptimal. The role of inflammation in DN has only recently been recognized. It has been shown that the NLRP3-inflammasome contributes to DN development by inducing interleukin (IL)-1β...

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Detalles Bibliográficos
Autores principales: Yuan, Fang, Kolb, Ryan, Pandey, Gaurav, Li, Wei, Sun, Lin, Liu, Fuyou, Sutterwala, Fayyaz S., Liu, Yinghong, Zhang, Weizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051905/
https://www.ncbi.nlm.nih.gov/pubmed/27706238
http://dx.doi.org/10.1371/journal.pone.0164135