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Extracellular Histone Released from Leukemic Cells Increases Their Adhesion to Endothelium and Protects them from Spontaneous and Chemotherapy-Induced Leukemic Cell Death

INTRODUCTION: When leukocytes are stimulated by reactive oxygen species (ROS), they release nuclear contents into the extracellular milieu, called by extracellular traps (ET). The nuclear contents are mainly composed of the histone–DNA complex and neutrophil elastase. This study investigated whether...

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Detalles Bibliográficos
Autores principales: Yoo, Hyun Ju, Lee, Jee-Soo, Kim, Ji-Eun, Gu, JaYoon, Koh, Youngil, Kim, Inho, Kim, Hyun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051947/
https://www.ncbi.nlm.nih.gov/pubmed/27706246
http://dx.doi.org/10.1371/journal.pone.0163982