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Production and purification of high-titer foamy virus vector for the treatment of leukocyte adhesion deficiency
Compared to other integrating viral vectors, foamy virus (FV) vectors have distinct advantages as a gene transfer tool, including their nonpathogenicity, the ability to carry larger transgene cassettes, and increased stability of virus particles due to DNA genome formation within the virions. Proof...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052019/ https://www.ncbi.nlm.nih.gov/pubmed/27722179 http://dx.doi.org/10.1038/mtm.2016.4 |