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CENPT bridges adjacent CENPA nucleosomes on young human α-satellite dimers

Nucleosomes containing the CenH3 (CENPA or CENP-A) histone variant replace H3 nucleosomes at centromeres to provide a foundation for kinetochore assembly. CENPA nucleosomes are part of the constitutive centromere associated network (CCAN) that forms the inner kinetochore on which outer kinetochore p...

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Detalles Bibliográficos
Autores principales: Thakur, Jitendra, Henikoff, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052034/
https://www.ncbi.nlm.nih.gov/pubmed/27384170
http://dx.doi.org/10.1101/gr.204784.116