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Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum

The malaria parasite Plasmodium falciparum has a great capacity for evolutionary adaptation to evade host immunity and develop drug resistance. Current understanding of parasite evolution is impeded by the fact that a large fraction of the genome is either highly repetitive or highly variable and th...

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Detalles Bibliográficos
Autores principales: Miles, Alistair, Iqbal, Zamin, Vauterin, Paul, Pearson, Richard, Campino, Susana, Theron, Michel, Gould, Kelda, Mead, Daniel, Drury, Eleanor, O'Brien, John, Ruano Rubio, Valentin, MacInnis, Bronwyn, Mwangi, Jonathan, Samarakoon, Upeka, Ranford-Cartwright, Lisa, Ferdig, Michael, Hayton, Karen, Su, Xin-zhuan, Wellems, Thomas, Rayner, Julian, McVean, Gil, Kwiatkowski, Dominic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052046/
https://www.ncbi.nlm.nih.gov/pubmed/27531718
http://dx.doi.org/10.1101/gr.203711.115