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Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin

The rates at which lesions are removed by DNA repair can vary widely throughout the genome, with important implications for genomic stability. To study this, we measured the distribution of nucleotide excision repair (NER) rates for UV-induced lesions throughout the budding yeast genome. By plotting...

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Detalles Bibliográficos
Autores principales: Yu, Shirong, Evans, Katie, van Eijk, Patrick, Bennett, Mark, Webster, Richard M., Leadbitter, Matthew, Teng, Yumin, Waters, Raymond, Jackson, Stephen P., Reed, Simon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052058/
https://www.ncbi.nlm.nih.gov/pubmed/27470111
http://dx.doi.org/10.1101/gr.209106.116