Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles

Alpha satellite is a tandemly organized type of repetitive DNA that comprises 5% of the genome and is found at all human centromeres. A defined number of 171-bp monomers are organized into chromosome-specific higher-order repeats (HORs) that are reiterated thousands of times. At least half of all hu...

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Detalles Bibliográficos
Autores principales: Aldrup-MacDonald, Megan E., Kuo, Molly E., Sullivan, Lori L., Chew, Kimberline, Sullivan, Beth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052062/
https://www.ncbi.nlm.nih.gov/pubmed/27510565
http://dx.doi.org/10.1101/gr.206706.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052062/
https://www.ncbi.nlm.nih.gov/pubmed/27510565
http://dx.doi.org/10.1101/gr.206706.116

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