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Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles
Alpha satellite is a tandemly organized type of repetitive DNA that comprises 5% of the genome and is found at all human centromeres. A defined number of 171-bp monomers are organized into chromosome-specific higher-order repeats (HORs) that are reiterated thousands of times. At least half of all hu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052062/ https://www.ncbi.nlm.nih.gov/pubmed/27510565 http://dx.doi.org/10.1101/gr.206706.116 |