Poly(ADP-ribose) polymerase 1 contributes to oxidative stress through downregulation of sirtuin 3 during cisplatin nephrotoxicity

Enhanced oxidative stress is a hallmark of cisplatin nephrotoxicity, and inhibition of poly(ADP-ribose) polymerase 1 (PARP1) attenuates oxidative stress during cisplatin nephrotoxicity; however, the precise mechanisms behind its action remain elusive. Here, using an in vitro model of cisplatin-induc...

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Detalles Bibliográficos
Autores principales: Yoon, Sang Pil, Kim, Jinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Anatomists 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052225/
https://www.ncbi.nlm.nih.gov/pubmed/27722009
http://dx.doi.org/10.5115/acb.2016.49.3.165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052225/
https://www.ncbi.nlm.nih.gov/pubmed/27722009
http://dx.doi.org/10.5115/acb.2016.49.3.165

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