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Differential transcriptional regulation of hypoxia-inducible factor-1α by arsenite under normoxia and hypoxia: involvement of Nrf2

ABSTRACT: Arsenite (As(III)) is widely distributed in nature and can be found in water, food, and air. There is significant evidence that exposure to As(III) is associated with human cancers originated from liver, lung, skin, bladder, kidney, and prostate. Hypoxia plays a role in tumor growth and ag...

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Detalles Bibliográficos
Autores principales: al Taleb, Zukaa, Petry, Andreas, Chi, Tabughang Franklin, Mennerich, Daniela, Görlach, Agnes, Dimova, Elitsa Y., Kietzmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052318/
https://www.ncbi.nlm.nih.gov/pubmed/27286880
http://dx.doi.org/10.1007/s00109-016-1439-7