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Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue

BACKGROUND: This study was designed to investigate whether ginsenoside Rb1 (Rb1) and compound K (CK) ameliorated insulin resistance by suppressing endoplasmic reticulum (ER) stress-induced inflammation in adipose tissue. METHODS: To induce ER stress, epididymal adipose tissue from mice or differenti...

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Detalles Bibliográficos
Autores principales: Chen, Weijie, Wang, Junlian, Luo, Yong, Wang, Tao, Li, Xiaochun, Li, Aiyun, Li, Jia, Liu, Kang, Liu, Baolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052408/
https://www.ncbi.nlm.nih.gov/pubmed/27746687
http://dx.doi.org/10.1016/j.jgr.2015.11.002