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Induction of Nrf2/ARE-mediated cytoprotective genes by red ginseng oil through ASK1–MKK4/7–JNK and p38 MAPK signaling pathways in HepG2 cells

BACKGROUND: The induction of cellular defensive genes such as phase II detoxifying and antioxidant enzymes is a highly effective strategy for protection against carcinogenesis as well as slowing cancer development. Transcription factor Nrf2 (nuclear factor E2-related factor 2) is responsible for act...

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Detalles Bibliográficos
Autores principales: Bak, Min Ji, Truong, Van-Long, Ko, Se-Yeon, Nguyen, Xuan Ngan Giang, Jun, Mira, Hong, Soon-Gi, Lee, Jong-Won, Jeong, Woo-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052443/
https://www.ncbi.nlm.nih.gov/pubmed/27746696
http://dx.doi.org/10.1016/j.jgr.2016.07.003