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Induction of Nrf2/ARE-mediated cytoprotective genes by red ginseng oil through ASK1–MKK4/7–JNK and p38 MAPK signaling pathways in HepG2 cells
BACKGROUND: The induction of cellular defensive genes such as phase II detoxifying and antioxidant enzymes is a highly effective strategy for protection against carcinogenesis as well as slowing cancer development. Transcription factor Nrf2 (nuclear factor E2-related factor 2) is responsible for act...
Autores principales: | Bak, Min Ji, Truong, Van-Long, Ko, Se-Yeon, Nguyen, Xuan Ngan Giang, Jun, Mira, Hong, Soon-Gi, Lee, Jong-Won, Jeong, Woo-Sik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052443/ https://www.ncbi.nlm.nih.gov/pubmed/27746696 http://dx.doi.org/10.1016/j.jgr.2016.07.003 |
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