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Investigation of LRRC8-Mediated Volume-Regulated Anion Currents in Xenopus Oocytes
Volume-regulated anion channels (VRACs) play an important role in controlling cell volume by opening upon cell swelling. Recent work has shown that heteromers of LRRC8A with other LRRC8 members (B, C, D, and E) form the VRAC. Here, we used Xenopus oocytes as a simple system to study LRRC8 proteins....
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052465/ https://www.ncbi.nlm.nih.gov/pubmed/27705766 http://dx.doi.org/10.1016/j.bpj.2016.08.030 |