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Investigation of LRRC8-Mediated Volume-Regulated Anion Currents in Xenopus Oocytes

Volume-regulated anion channels (VRACs) play an important role in controlling cell volume by opening upon cell swelling. Recent work has shown that heteromers of LRRC8A with other LRRC8 members (B, C, D, and E) form the VRAC. Here, we used Xenopus oocytes as a simple system to study LRRC8 proteins....

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Detalles Bibliográficos
Autores principales:	Gaitán-Peñas, Héctor, Gradogna, Antonella, Laparra-Cuervo, Lara, Solsona, Carles, Fernández-Dueñas, Victor, Barrallo-Gimeno, Alejandro, Ciruela, Francisco, Lakadamyali, Melike, Pusch, Michael, Estévez, Raúl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2016
Materias:	Channels and Transporters
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052465/ https://www.ncbi.nlm.nih.gov/pubmed/27705766 http://dx.doi.org/10.1016/j.bpj.2016.08.030

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