Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer’s disease treatment

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by genotypic and phenotypic heterogeneity. Critical components of the two AD pathological pathways, Aβ-amyloidosis and Tauopathy, have been considered as therapeutic targets. Among them, much effort is focused on aberrant Tau phos...

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Detalles Bibliográficos
Autores principales: Sun, Wenchao, Lee, Seongsoo, Huang, Xiaoran, Liu, Song, Inayathullah, Mohammed, Kim, Kwang-Min, Tang, Hongxiang, Ashford, J. Wesson, Rajadas, Jayakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052533/
https://www.ncbi.nlm.nih.gov/pubmed/27708431
http://dx.doi.org/10.1038/srep34784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052533/
https://www.ncbi.nlm.nih.gov/pubmed/27708431
http://dx.doi.org/10.1038/srep34784

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