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Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer’s disease treatment
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by genotypic and phenotypic heterogeneity. Critical components of the two AD pathological pathways, Aβ-amyloidosis and Tauopathy, have been considered as therapeutic targets. Among them, much effort is focused on aberrant Tau phos...
Autores principales: | Sun, Wenchao, Lee, Seongsoo, Huang, Xiaoran, Liu, Song, Inayathullah, Mohammed, Kim, Kwang-Min, Tang, Hongxiang, Ashford, J. Wesson, Rajadas, Jayakumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052533/ https://www.ncbi.nlm.nih.gov/pubmed/27708431 http://dx.doi.org/10.1038/srep34784 |
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