ERK/c-Jun Recruits Tet1 to Induce Zta Expression and Epstein-Barr Virus Reactivation through DNA Demethylation

DNA demethylation plays an essential role in the reactivation of Epstein-Barr virus (EBV) from latency infection. However, it is unclear how epigenetic modification is initiated in responding to stimuli. Here, we demonstrate that ERK/c-Jun signaling is involved in DNA demethylation of EBV immediate...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Han, Dongjie, Wan, Pin, Pan, Pan, Cao, Yanhua, Liu, Yingle, Wu, Kailang, Wu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052586/
https://www.ncbi.nlm.nih.gov/pubmed/27708396
http://dx.doi.org/10.1038/srep34543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052586/
https://www.ncbi.nlm.nih.gov/pubmed/27708396
http://dx.doi.org/10.1038/srep34543

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