CXCL13/CXCR5 enhances sodium channel Nav1.8 current density via p38 MAP kinase in primary sensory neurons following inflammatory pain

CXCL13 is a B lymphocyte chemoattractant and activates CXCR5 receptor in the immune system. Here we investigated whether CXCL13/CXCR5 mediates inflammatory pain in dorsal root ganglia (DRG) and the underlying mechanisms. Peripheral injection of complete Freund’s Adjuvant (CFA) increased the expressi...

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Detalles Bibliográficos
Autores principales: Wu, Xiao-Bo, Cao, De-Li, Zhang, Xin, Jiang, Bao-Chun, Zhao, Lin-Xia, Qian, Bin, Gao, Yong-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052602/
https://www.ncbi.nlm.nih.gov/pubmed/27708397
http://dx.doi.org/10.1038/srep34836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052602/
https://www.ncbi.nlm.nih.gov/pubmed/27708397
http://dx.doi.org/10.1038/srep34836

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