Replenishment of microRNA-188-5p restores the synaptic and cognitive deficits in 5XFAD Mouse Model of Alzheimer’s Disease

MicroRNAs have emerged as key factors in development, neurogenesis and synaptic functions in the central nervous system. In the present study, we investigated a pathophysiological significance of microRNA-188-5p (miR-188-5p) in Alzheimer’s disease (AD). We found that oligomeric Aβ(1-42) treatment di...

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Detalles Bibliográficos
Autores principales: Lee, Kihwan, Kim, Hyunju, An, Kyongman, Kwon, Oh-Bin, Park, Sungjun, Cha, Jin Hee, Kim, Myoung-Hwan, Lee, Yoontae, Kim, Joung-Hun, Cho, Kwangwook, Kim, Hye-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052619/
https://www.ncbi.nlm.nih.gov/pubmed/27708404
http://dx.doi.org/10.1038/srep34433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052619/
https://www.ncbi.nlm.nih.gov/pubmed/27708404
http://dx.doi.org/10.1038/srep34433

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