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MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis

MicroRNA-155 (miR-155) is an important regulator of B cells in mice. B cells have a critical role in the pathogenesis of rheumatoid arthritis (RA). Here we show that miR-155 is highly expressed in peripheral blood B cells from RA patients compared with healthy individuals, particularly in the IgD(-)...

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Detalles Bibliográficos
Autores principales: Alivernini, Stefano, Kurowska-Stolarska, Mariola, Tolusso, Barbara, Benvenuto, Roberta, Elmesmari, Aziza, Canestri, Silvia, Petricca, Luca, Mangoni, Antonella, Fedele, Anna Laura, Di Mario, Clara, Gigante, Maria Rita, Gremese, Elisa, McInnes, Iain B., Ferraccioli, Gianfranco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052655/
https://www.ncbi.nlm.nih.gov/pubmed/27671860
http://dx.doi.org/10.1038/ncomms12970