Satellite RNAs promote pancreatic oncogenic processes via the dysfunction of YBX1

Highly repetitive tandem arrays at the centromeric and pericentromeric regions in chromosomes, previously considered silent, are actively transcribed, particularly in cancer. This aberrant expression occurs even in K-ras-mutated pancreatic intraepithelial neoplasia (PanIN) tissues, which are precanc...

Descripción completa

Detalles Bibliográficos
Autores principales: Kishikawa, Takahiro, Otsuka, Motoyuki, Yoshikawa, Takeshi, Ohno, Motoko, Ijichi, Hideaki, Koike, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052683/
https://www.ncbi.nlm.nih.gov/pubmed/27667193
http://dx.doi.org/10.1038/ncomms13006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052683/
https://www.ncbi.nlm.nih.gov/pubmed/27667193
http://dx.doi.org/10.1038/ncomms13006

Ejemplares similares