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ApoE deficiency promotes colon inflammation and enhances the inflammatory potential of oxidized-LDL and TNF-α in primary colon epithelial cells

Although deficiency in Apolipoprotein E (ApoE) is linked to many diseases, its effect on colon homoeostasis remains unknown. ApoE appears to control inflammation by regulating nuclear factor-κB (NF-κB). The present study was designed to examine whether ApoE deficiency affects factors of colon integr...

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Detalles Bibliográficos
Autores principales: El-Bahrawy, Ali H., Tarhuni, Abdelmetalab, Kim, Hogyoung, Subramaniam, Venkat, Benslimane, Ilyes, Elmajeed, Zakaria Y. Abd, Okpechi, Samuel C., Ghonim, Mohamed A., Hemeida, Ramadan A.M., Abo-yousef, Amira M., El-Sherbiny, Gamal A., Abdel-Raheem, Ihab T., Kim, Jong, Naura, Amarjit S., Boulares, A. Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052706/
https://www.ncbi.nlm.nih.gov/pubmed/27538678
http://dx.doi.org/10.1042/BSR20160195