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Anti-citrullinated protein antibodies and high levels of rheumatoid factor are associated with systemic bone loss in patients with early untreated rheumatoid arthritis

BACKGROUND: Autoantibodies such as anti-citrullinated protein antibodies (ACPA) are major risk factors for articular bone destruction from the earliest phases of rheumatoid arthritis (RA). The aim of the current study was to determine whether RA-associated autoantibodies also impact on systemic bone...

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Detalles Bibliográficos
Autores principales: Bugatti, Serena, Bogliolo, Laura, Vitolo, Barbara, Manzo, Antonio, Montecucco, Carlomaurizio, Caporali, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052789/
https://www.ncbi.nlm.nih.gov/pubmed/27716332
http://dx.doi.org/10.1186/s13075-016-1116-9