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Spinal cord injury induces astroglial conversion towards neuronal lineage

BACKGROUND: Neurons have intrinsic capability to regenerate after lesion, though not spontaneously. Spinal cord injury (SCI) causes permanent neurological impairments partly due to formation of a glial scar that is composed of astrocytes and microglia. Astrocytes play both beneficial and detrimental...

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Detalles Bibliográficos
Autores principales: Noristani, Harun Najib, Sabourin, Jean Charles, Boukhaddaoui, Hassan, Chan-Seng, Emilie, Gerber, Yannick Nicolas, Perrin, Florence Evelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052929/
https://www.ncbi.nlm.nih.gov/pubmed/27716282
http://dx.doi.org/10.1186/s13024-016-0133-0