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Boolean regulatory network reconstruction using literature based knowledge with a genetic algorithm optimization method
BACKGROUND: Prior knowledge networks (PKNs) provide a framework for the development of computational biological models, including Boolean models of regulatory networks which are the focus of this work. PKNs are created by a painstaking process of literature curation, and generally describe all relev...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053080/ https://www.ncbi.nlm.nih.gov/pubmed/27716031 http://dx.doi.org/10.1186/s12859-016-1287-z |