TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte‐derived dendritic cells

Intracerebral levels of Transforming Growth Factor beta (TGFβ) rise rapidly during the onset of experimental autoimmune encephalomyelitis (EAE), a mouse model of Multiple Sclerosis (MS). We addressed the role of TGFβ responsiveness in EAE by targeting the TGFβ receptor in myeloid cells, determining...

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Detalles Bibliográficos
Autores principales: Parsa, Roham, Lund, Harald, Tosevski, Ivana, Zhang, Xing‐Mei, Malipiero, Ursula, Beckervordersandforth, Jan, Merkler, Doron, Prinz, Marco, Gyllenberg, Alexandra, James, Tojo, Warnecke, Andreas, Hillert, Jan, Alfredsson, Lars, Kockum, Ingrid, Olsson, Tomas, Fontana, Adriano, Suter, Tobias, Harris, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053226/
https://www.ncbi.nlm.nih.gov/pubmed/27479807
http://dx.doi.org/10.1002/glia.23033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053226/
https://www.ncbi.nlm.nih.gov/pubmed/27479807
http://dx.doi.org/10.1002/glia.23033

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