Comprehensive characterization of ligand‐induced plasticity changes in a dimeric enzyme

An enzyme's inherent structural plasticity is frequently associated with substrate binding, yet detailed structural characterization of flexible proteins remains challenging. This study employs complementary biophysical methods to characterize the partially unfolded structure of substrate‐free...

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Detalles Bibliográficos
Autores principales: Baettig, Oliver M., Shi, Kun, Yachnin, Brahm J., Burk, David L., Berghuis, Albert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053276/
https://www.ncbi.nlm.nih.gov/pubmed/27333541
http://dx.doi.org/10.1111/febs.13788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053276/
https://www.ncbi.nlm.nih.gov/pubmed/27333541
http://dx.doi.org/10.1111/febs.13788

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